|ZFIN ID: ZDB-PUB-110103-4|
Zebrafish models of the immune response: taking it on the ChIn
Renshaw, S.A., and Ingham, P.W.
|Source:||BMC Biology 8(1): 148 (Other)|
|Registered Authors:||Ingham, Philip, Renshaw, Steve A.|
|PubMed:||21176245 Full text @ BMC Biol.|
Renshaw, S.A., and Ingham, P.W. (2010) Zebrafish models of the immune response: taking it on the ChIn. BMC Biology. 8(1):148.
ABSTRACTThe zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stimulus required to induce the inflammatory response. A new chemically induced inflammation assay ('ChIn' assay) published in BMC Biology obviates this requirement and seems set to accelerate progress in the field.
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