PUBLICATION

Maternal nodal and zebrafish embryogenesis

Authors
Bennett, J.T., Stickney, H.L., Choi, W.Y., Ciruna, B., Talbot, W.S., and Schier, A.F.
ID
ZDB-PUB-071118-29
Date
2007
Source
Nature   450(7167): E1-E4 (Journal)
Registered Authors
Bennett, Jimmy, Choi, Wen-Yee, Ciruna, Brian, Schier, Alexander, Stickney, Heather, Talbot, William S.
Keywords
none
MeSH Terms
  • Animals
  • Body Patterning*
  • Embryo, Nonmammalian/metabolism
  • Female
  • Intracellular Signaling Peptides and Proteins/genetics
  • Intracellular Signaling Peptides and Proteins/metabolism*
  • Models, Biological
  • Mothers
  • Nodal Signaling Ligands
  • Ovary/metabolism
  • Ovum/metabolism
  • RNA Splicing
  • Reproducibility of Results
  • Zebrafish/embryology*
  • Zebrafish/genetics
  • Zebrafish/metabolism
  • Zebrafish Proteins/genetics
  • Zebrafish Proteins/metabolism*
PubMed
17994032 Full text @ Nature
Abstract
In fish and amphibians, the dorsal axis is specified by the asymmetric localization of maternally provided components of the Wnt signalling pathway. Gore et al. suggest that the Nodal signal Squint (Sqt) is required as a maternally provided dorsal determinant in zebrafish. Here we test their proposal and show that the maternal activities of sqt and the related Nodal gene cyclops (cyc) are not required for dorsoventral patterning.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes