ZFIN ID: ZDB-PUB-061108-11
The HeArt of Regeneration
Curado, S., and Stainier, D.Y.
Date: 2006
Source: Cell 127(3): 462-464 (Journal)
Registered Authors: Stainier, Didier
Keywords: none
MeSH Terms: Animals; Animals, Genetically Modified; Animals, Outbred Strains; Cell Differentiation; Heart/physiology* (all 19) expand
PubMed: 17081969 Full text @ Cell
ABSTRACT
Fish and amphibian hearts are known to regenerate after partial resection, but the molecular mechanisms underlying this process remain unclear. In this issue of Cell, analyze regeneration in the zebrafish heart. Their work indicates that new cardiomyocytes originate from undifferentiated progenitor cells and reveals a critical role for the epicardium, the cellular layer that covers the heart.
ADDITIONAL INFORMATIONNo data available