PUBLICATION

The genetics of hearing and balance in zebrafish

Authors
Nicolson, T.
ID
ZDB-PUB-051116-3
Date
2005
Source
Annual review of genetics   39: 9-22 (Review)
Registered Authors
Nicolson, Teresa
Keywords
none
MeSH Terms
  • Animals
  • Ear, Inner/anatomy & histology
  • Ear, Inner/embryology
  • Ear, Inner/metabolism
  • Hair Cells, Auditory/physiology
  • Hearing/genetics*
  • Hearing/physiology*
  • Mechanotransduction, Cellular
  • Postural Balance
  • Zebrafish/anatomy & histology
  • Zebrafish/genetics*
  • Zebrafish/physiology*
PubMed
16285850 Full text @ Annu. Rev. Genet.
Abstract
The zebrafish is an excellent model system for studying the molecular basis of inner ear development and function. The eggs develop ex utero and the ear is transparent for the first few weeks of life. Forward genetic screens and antisense technology have helped to elucidate the signaling pathways and molecules required for inner ear development and function. This review addresses the most recent advances in our understanding of how the ear forms and discusses the molecules in hair cells that are essential for sensing sound and movement in the zebrafish.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes