Morpholino

MO6-gja1b

ID

ZDB-MRPHLNO-201130-2

Name

MO6-gja1b

Previous Names

None

Target

gja1b (1)

Sequence

5' - TCCCAACGCACTCCAGTCACCCATC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO6-gja1b

No data available

Phenotype

Phenotype resulting from MO6-gja1b

Phenotype	Fish	Figures
cardiac ventricle decreased contractility, abnormal	AB/TU + MO6-gja1b	Fig. 6 from Rattka et al., 2021
central canal cerebrospinal fluid circulation decreased process quality, abnormal	AB + MO6-gja1b	Fig. 3 from Zhang et al., 2020
ependymal cell calcium-mediated signaling decreased occurrence, abnormal	cms5Tg + MO6-gja1b	Fig. 4 from Zhang et al., 2020
ependymal cell cilium movement decreased occurrence, abnormal	hsc5Tg + MO6-gja1b	Fig. 3 from Zhang et al., 2020
ependymal cell motile cilium assembly decreased occurrence, abnormal	AB + MO6-gja1b	Fig. 3 , Fig. 4 from Zhang et al., 2020
heart decreased functionality, abnormal	AB/TU + MO6-gja1b	Fig. 6 from Rattka et al., 2021
heart contraction decreased rate, abnormal	AB/TU + MO6-gja1b	Fig. 5 , Fig. 6 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO6-gja1b	Fig. 5 from Rattka et al., 2021
spinal cord has fewer parts of type ependymal cell motile cilium, abnormal	AB + MO6-gja1b	Fig. 3 , Fig. 4 from Zhang et al., 2020
spinal cord ependymal cell GCaMP expression decreased amount, abnormal	cms5Tg + MO6-gja1b	Fig. 4 from Zhang et al., 2020

Phenotype of all Fish created by or utilizing MO6-gja1b

Phenotype	Fish	Conditions	Figures
spinal cord has number of ependymal cell motile cilium, ameliorated	AB + MO6-gja1b	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 4 from Zhang et al., 2020
ependymal cell motile cilium assembly occurrence, ameliorated	AB + MO6-gja1b	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 4 from Zhang et al., 2020
ependymal cell motile cilium assembly decreased occurrence, abnormal	AB + MO6-gja1b	standard conditions	Fig. 3 , Fig. 4 from Zhang et al., 2020
central canal cerebrospinal fluid circulation decreased process quality, abnormal	AB + MO6-gja1b	standard conditions	Fig. 3 from Zhang et al., 2020
spinal cord has fewer parts of type ependymal cell motile cilium, abnormal	AB + MO6-gja1b	standard conditions	Fig. 3 , Fig. 4 from Zhang et al., 2020
heart contraction decreased rate, abnormal	AB/TU + MO6-gja1b	standard conditions	Fig. 5 , Fig. 6 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO6-gja1b	standard conditions	Fig. 5 from Rattka et al., 2021
heart decreased functionality, abnormal	AB/TU + MO6-gja1b	standard conditions	Fig. 6 from Rattka et al., 2021
cardiac ventricle decreased contractility, abnormal	AB/TU + MO6-gja1b	standard conditions	Fig. 6 from Rattka et al., 2021
spinal cord ependymal cell GCaMP expression decreased amount, abnormal	cms5Tg + MO6-gja1b	standard conditions	Fig. 4 from Zhang et al., 2020
ependymal cell calcium-mediated signaling decreased occurrence, abnormal	cms5Tg + MO6-gja1b	standard conditions	Fig. 4 from Zhang et al., 2020
ependymal cell calcium-mediated signaling occurrence, ameliorated	cms5Tg + MO6-gja1b	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 4 from Zhang et al., 2020
ependymal cell cilium movement decreased occurrence, abnormal	hsc5Tg + MO6-gja1b	standard conditions	Fig. 3 from Zhang et al., 2020
heart decreased functionality, abnormal	AB/TU + MO2-spen + MO6-gja1b	standard conditions	Fig. 7 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO2-spen + MO6-gja1b	standard conditions	Fig. 7 from Rattka et al., 2021

Citations