Morpholino

MO2-irs1

ID

ZDB-MRPHLNO-180717-1

Name

MO2-irs1

Previous Names

None

Target

irs1 (1)

Sequence

5' - ACAGAAAAATTGCAGGATCGGAAGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-irs1

No data available

Phenotype

Phenotype resulting from MO2-irs1

Phenotype	Fish	Figures
developmental growth decreased rate, abnormal	WT + MO2-irs1	Fig. 3 from Kamei et al., 2018
neural crest ab5-akt labeling decreased amount, abnormal	WT + MO2-irs1	Fig. 5 from Kamei et al., 2018
whole organism ab7-mapk labeling decreased amount, abnormal	WT + MO2-irs1	Fig. 4 from Kamei et al., 2018
whole organism ab2-akt labeling decreased amount, abnormal	WT + MO2-irs1	Fig. 4 from Kamei et al., 2018

Phenotype of all Fish created by or utilizing MO2-irs1

Phenotype	Fish	Conditions	Figures
neural crest ab5-akt labeling decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
whole organism ab7-mapk labeling decreased amount, abnormal	WT + MO2-irs1	control	Fig. 4 from Kamei et al., 2018
pharyngeal arch mesenchyme derived from head neural crest dlx2a expression decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
whole organism pdgfrb expression decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
neural crest ab5-akt labeling decreased amount, abnormal	WT + MO2-irs1	control	Fig. 5 from Kamei et al., 2018
neural crest cell death increased occurrence, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
whole organism anterior region ab1-casp3 labeling increased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
developmental growth decreased rate, abnormal	WT + MO2-irs1	hypoxia	Fig. 3 from Kamei et al., 2018
neural crest ab1-casp3 labeling increased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
cell death occurrence, ameliorated	WT + MO2-irs1	hypoxia, chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F	Fig. 6 from Kamei et al., 2018
whole organism ngfra expression decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
whole organism ab2-akt labeling decreased amount, abnormal	WT + MO2-irs1	control	Fig. 4 from Kamei et al., 2018
developmental growth decreased rate, abnormal	WT + MO2-irs1	control	Fig. 3 from Kamei et al., 2018
whole organism ab7-mapk labeling decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 4 from Kamei et al., 2018
whole organism ab2-akt labeling decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 4 from Kamei et al., 2018
brain dlx2a expression decreased amount, abnormal	WT + MO2-irs1	hypoxia	Fig. 5 from Kamei et al., 2018
cell death increased occurrence, abnormal	WT + MO2-irs1	hypoxia	Fig. 6 from Kamei et al., 2018
developmental growth decreased rate, abnormal	WT + MO2-irs1	oxygen content, hypoxia	Fig. 3 from Kamei et al., 2018

Citations