ZFIN Morpholino: MO2-thrb

Target Location

Genome Build: GRCz11Chromosome: 19

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-thrb

No data available

Phenotype

Phenotype resulting from MO2-thrb

Phenotype	Fish	Figures
horizontal cell synapse increased amount, abnormal	kj9Tg; mi2007Tg + MO2-thrb	Fig. 5 from Yoshimatsu et al., 2014
red sensitive photoreceptor cell ab3-rho labeling decreased amount, abnormal	WT + MO2-thrb	Fig. 2 , Fig. 3 from DuVal et al., 2018
red sensitive photoreceptor cell decreased amount, abnormal	WT + MO2-thrb	Fig. 2 , Fig. 3 from DuVal et al., 2018
UV sensitive photoreceptor cell ab1-10c9.1 labeling increased amount, abnormal	WT + MO2-thrb	Fig. 2 , Fig. 3 from DuVal et al., 2018
UV sensitive photoreceptor cell increased amount, abnormal	WT + MO2-thrb	Fig. 2 , Fig. 3 from DuVal et al., 2018 Fig. 5 from Yoshimatsu et al., 2014

Phenotype of all Fish created by or utilizing MO2-thrb

Phenotype	Fish	Conditions	Figures
red sensitive photoreceptor cell decreased amount, abnormal	WT + MO2-thrb	standard conditions	Fig. 2 , Fig. 3 from DuVal et al., 2018
red sensitive photoreceptor cell ab3-rho labeling decreased amount, abnormal	WT + MO2-thrb	standard conditions	Fig. 2 , Fig. 3 from DuVal et al., 2018
UV sensitive photoreceptor cell ab1-10c9.1 labeling increased amount, abnormal	WT + MO2-thrb	standard conditions	Fig. 2 , Fig. 3 from DuVal et al., 2018
UV sensitive photoreceptor cell increased amount, abnormal	WT + MO2-thrb	standard conditions	Fig. 2 , Fig. 3 from DuVal et al., 2018
horizontal cell synapse increased amount, abnormal	kj9Tg; mi2007Tg + MO2-thrb	control	Fig. 5 from Yoshimatsu et al., 2014
UV sensitive photoreceptor cell increased amount, abnormal	kj9Tg; mi2007Tg + MO2-thrb	control	Fig. 5 from Yoshimatsu et al., 2014
retina morphology, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
retinal photoreceptor layer morphology, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
red sensitive photoreceptor cell decreased amount, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
retinal photoreceptor layer perforate, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
red sensitive photoreceptor cell ab3-rho labeling decreased amount, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
UV sensitive photoreceptor cell decreased amount, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
UV sensitive photoreceptor cell ab1-10c9.1 labeling decreased amount, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018
blue sensitive photoreceptor cell decreased amount, abnormal	gdf6a^s327/s327 + MO2-thrb	standard conditions	Fig. 2 from DuVal et al., 2018

Citations

Include unpublished citations

DuVal, M.G., Allison, W.T. (2018) Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes. Investigative ophthalmology & visual science. 59:6089-6101
Yoshimatsu, T., Williams, P.R., D'Orazi, F.D., Suzuki, S.C., Fadool, J.M., Allison, W.T., Raymond, P.A., Wong, R.O. (2014) Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells. Nature communications. 5:3699
Suzuki, S.C., Bleckert, A., Williams, P.R., Takechi, M., Kawamura, S., and Wong, R.O. (2013) Cone photoreceptor types in zebrafish are generated by symmetric terminal divisions of dedicated precursors. Proceedings of the National Academy of Sciences of the United States of America. 110(37):15109-14

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