Morpholino

MO4-jag1a

ID

ZDB-MRPHLNO-121129-2

Name

MO4-jag1a

Previous Names

jag1a spl MO (1)

Target

jag1a (1)

Sequence

5' - AAACAGCCTCTGAAACTCACCGGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-jag1a

Expressed Gene	Anatomy	Figures
nkx2.4b	hypothalamus pharyngeal endoderm thyroid follicle thyroid primordium	Fig. 7 from Porazzi et al., 2012
slc5a5	thyroid follicle	Fig. 7 from Porazzi et al., 2012
tg	thyroid follicle thyroid primordium	Fig. 7 from Porazzi et al., 2012

Phenotype

Phenotype resulting from MO4-jag1a

Phenotype	Fish	Figures
ceratohyal cartilage decreased size, abnormal	WT + MO4-jag1a	Fig. S5 from Porazzi et al., 2012
embryonic viscerocranium morphogenesis decreased process quality, abnormal	WT + MO4-jag1a	Fig. S5 from Porazzi et al., 2012
endocrine system has fewer parts of type thyroid follicle, abnormal	WT + MO4-jag1a	Fig. 7 from Porazzi et al., 2012
Meckel's cartilage decreased size, abnormal	WT + MO4-jag1a	Fig. S5 from Porazzi et al., 2012
palatoquadrate cartilage decreased size, abnormal	WT + MO4-jag1a	Fig. S5 from Porazzi et al., 2012
thyroid gland development decreased process quality, abnormal	WT + MO4-jag1a	Fig. 7 from Porazzi et al., 2012

Phenotype of all Fish created by or utilizing MO4-jag1a

Phenotype	Fish	Conditions	Figures
embryonic viscerocranium morphogenesis decreased process quality, abnormal	WT + MO4-jag1a	standard conditions	Fig. S5 from Porazzi et al., 2012
ceratohyal cartilage decreased size, abnormal	WT + MO4-jag1a	standard conditions	Fig. S5 from Porazzi et al., 2012
palatoquadrate cartilage decreased size, abnormal	WT + MO4-jag1a	standard conditions	Fig. S5 from Porazzi et al., 2012
thyroid gland development decreased process quality, abnormal	WT + MO4-jag1a	standard conditions	Fig. 7 from Porazzi et al., 2012
Meckel's cartilage decreased size, abnormal	WT + MO4-jag1a	standard conditions	Fig. S5 from Porazzi et al., 2012
endocrine system has fewer parts of type thyroid follicle, abnormal	WT + MO4-jag1a	standard conditions	Fig. 7 from Porazzi et al., 2012
pharyngeal endoderm nkx2.4b expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
caudal fin truncated, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
notochord morphology, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
thyroid stimulating hormone secreting cell tshba expression increased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 3 from de Filippis et al., 2016
whole organism anterior-posterior axis decreased length, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
thyroid follicle slc5a5 expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
thyroid primordium aplastic/hypoplastic, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
thyroid primordium tg expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
whole organism tshba expression increased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 3 from de Filippis et al., 2016
caudal fin kinked, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
thyroid primordium slc5a5 expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2 from de Filippis et al., 2016
whole organism tg expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 3 from de Filippis et al., 2016
thyroid follicle tg expression decreased amount, abnormal	AB + MO3-jag1b + MO4-jag1a	standard conditions	Fig. 2, Fig. 3 from de Filippis et al., 2016

Citations