Morpholino

MO3-nrg1

ID
ZDB-MRPHLNO-111026-1
Name
MO3-nrg1
Previous Names
None
Target
Sequence
5' - GATGCGGATTTGCGGCAATACCTGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking MO. This morpholino knocks down all isoforms of Nrg1. Targeted to the exon-intron boundary of the first exon of the common EGF domain. -- ( Perlin et al. ZDB-PUB-111019-16 )
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-nrg1
No data available
Phenotype
Phenotype resulting from MO3-nrg1
Phenotype Fish Figures
peripheral nervous system myelin formation decreased occurrence, abnormal zf15Tg + MO3-nrg1 Fig. 1 with image from Perlin et al., 2011
posterior lateral line nerve lacks parts or has fewer parts of type myelinating Schwann cell, abnormal zf15Tg + MO3-nrg1 Fig. 1 with image from Perlin et al., 2011
Phenotype of all Fish created by or utilizing MO3-nrg1
Phenotype Fish Conditions Figures
posterior lateral line nerve lacks parts or has fewer parts of type myelinating Schwann cell, abnormal zf15Tg + MO3-nrg1 standard conditions Fig. 1 with image from Perlin et al., 2011
peripheral nervous system myelin formation decreased occurrence, abnormal zf15Tg + MO3-nrg1 standard conditions Fig. 1 with image from Perlin et al., 2011
Citations
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