Morpholino

MO1-cdk5rap3

ID
ZDB-MRPHLNO-110609-3
Name
MO1-cdk5rap3
Previous Names
  • lzap-5'-UTR MO (1)
  • MO1-cdkrap3 (1)
Target
Sequence
5' - AAGAATTACTAAAACGACCCCATGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO. Targets the 5'UTR.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-cdk5rap3
Expressed Gene Anatomy Figures
axin2 Fig. 5,  Fig. 6 from Lin et al., 2015
bmp2b Fig. 2,  Fig. 4 from Lin et al., 2015
Fig. 5 with image from Liu et al., 2011
bmp4 Fig. 2 from Lin et al., 2015
bmp7a Fig. 2,  Fig. S6 from Lin et al., 2015
chrd Fig. 2,  Fig. 4,  Fig. 6 from Lin et al., 2015
ctslb Fig. 5 with image from Liu et al., 2011
dharma Fig. 5 from Lin et al., 2015
eve1 Fig. 5 with image from Liu et al., 2011
fgf3 Fig. 5,  Fig. 6 from Lin et al., 2015
fgf8a Fig. 5,  Fig. 6 from Lin et al., 2015
nog1 Fig. 2 from Lin et al., 2015
sp5l Fig. 5,  Fig. 6 from Lin et al., 2015
tbxta Fig. 5 with image from Liu et al., 2011
Phenotype
Phenotype resulting from MO1-cdk5rap3
Phenotype Fish Figures
blastoderm cell cellular adhesivity blastoderm cell, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
blastoderm cell decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
blastoderm cell increased size, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
blastoderm cell nucleus decreased amount, abnormal AB + MO1-cdk5rap3 Fig. S3 with image from Liu et al., 2011
blastoderm cell nucleus increased size, abnormal AB + MO1-cdk5rap3 Fig. S3 with image from Liu et al., 2011
caudal fin shortened, abnormal AB + MO1-cdk5rap3 Fig. 1 from Lin et al., 2015
caudal fin ventral region aplastic/hypoplastic, abnormal AB + MO1-cdk5rap3 Fig. 1 from Lin et al., 2015
cell population proliferation decreased occurrence, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
embryo development arrested, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
embryonic cleavage arrested, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
embryonic cleavage delayed, abnormal AB + MO1-cdk5rap3 Fig. 3 with image from Liu et al., 2011
epiboly involved in gastrulation with mouth forming second arrested, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
epiboly involved in gastrulation with mouth forming second decreased rate, abnormal AB + MO1-cdk5rap3 Fig. 3 with image from Liu et al., 2011
epiboly involved in gastrulation with mouth forming second delayed, abnormal AB + MO1-cdk5rap3 Fig. S1 from Lin et al., 2015
G2/M transition of mitotic cell cycle delayed, abnormal AB + MO1-cdk5rap3 Fig. 5 with image from Liu et al., 2011
gastrulation decreased rate, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
intrinsic apoptotic signaling pathway increased process quality, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
mitotic cell cycle decreased occurrence, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
mitotic cell cycle delayed, abnormal AB + MO1-cdk5rap3 Fig. 5 with image from Liu et al., 2011
trunk posterior region shortened, abnormal AB + MO1-cdk5rap3 Fig. 1 from Lin et al., 2015
whole organism apoptotic, abnormal AB + MO1-cdk5rap3 Fig. 4 with image from Liu et al., 2011
whole organism bmp2b expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism dharma expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 5 from Lin et al., 2015
whole organism bmp7a expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism bmp4 expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism decreased life span, abnormal AB + MO1-cdk5rap3 Fig. 1,  Fig. S1 from Lin et al., 2015
whole organism dorsalized, abnormal AB + MO1-cdk5rap3 Fig. 1,  Fig. 3,  Fig. S8,  Fig. S9 from Lin et al., 2015
whole organism hypoplastic, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism fgf3 expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism ab1-ctnnb labeling increased amount, abnormal AB + MO1-cdk5rap3 Fig. 7 from Lin et al., 2015
whole organism sp5l expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism bmp7a expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. S6 from Lin et al., 2015
whole organism axin2 expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism ab2-gsk3 labeling increased amount, abnormal AB + MO1-cdk5rap3 Fig. 7 from Lin et al., 2015
whole organism fgf8a expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism ab2-mapk labeling increased amount, abnormal AB + MO1-cdk5rap3 Fig. S7 from Lin et al., 2015
whole organism chrd expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 2,  Fig. 6 from Lin et al., 2015
whole organism ab1-ctnnb labeling increased distribution, abnormal AB + MO1-cdk5rap3 Fig. 7 from Lin et al., 2015
whole organism morphology, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism viability, abnormal AB + MO1-cdk5rap3 Fig. 3 with image from Liu et al., 2011
whole organism anterior-posterior axis decreased length, abnormal AB + MO1-cdk5rap3 Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism dorsal region dharma expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 5 from Lin et al., 2015
whole organism dorsal region ab2-mapk labeling increased amount, abnormal AB + MO1-cdk5rap3 Fig. 5 from Lin et al., 2015
whole organism dorsal region chrd expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 2,  Fig. 4 from Lin et al., 2015
whole organism dorsal region nog1 expression increased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism dorsal region ab2-mapk labeling increased distribution, abnormal AB + MO1-cdk5rap3 Fig. 5 from Lin et al., 2015
whole organism dorsal region chrd expression increased distribution, abnormal AB + MO1-cdk5rap3 Fig. 2,  Fig. 4,  Fig. 6 from Lin et al., 2015
whole organism dorsal region nog1 expression increased distribution, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region ab1-smad labeling decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region bmp2b expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region bmp7a expression decreased amount, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region bmp7a expression decreased distribution, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region bmp2b expression decreased distribution, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
whole organism ventral region ab1-smad labeling decreased distribution, abnormal AB + MO1-cdk5rap3 Fig. 2 from Lin et al., 2015
Phenotype of all Fish created by or utilizing MO1-cdk5rap3
Phenotype Fish Conditions Figures
blastoderm cell increased size, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
whole organism hypoplastic, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism bmp7a expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. S6 from Lin et al., 2015
gastrulation decreased rate, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism ventral region bmp7a expression decreased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
intrinsic apoptotic signaling pathway increased process quality, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
epiboly involved in gastrulation with mouth forming second decreased rate, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image from Liu et al., 2011
whole organism bmp2b expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism fgf3 expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5,  Fig. 6 from Lin et al., 2015
mitotic cell cycle decreased occurrence, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
whole organism ventral region bmp2b expression decreased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism dorsal region nog1 expression increased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
embryonic cleavage delayed, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image from Liu et al., 2011
whole organism ab1-ctnnb labeling increased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 7 from Lin et al., 2015
whole organism dorsalized, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 1,  Fig. 3,  Fig. S8,  Fig. S9 from Lin et al., 2015
caudal fin shortened, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 1 from Lin et al., 2015
whole organism ventral region bmp2b expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism viability, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image from Liu et al., 2011
whole organism ventral region bmp7a expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism dorsal region dharma expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 from Lin et al., 2015
whole organism ab2-mapk labeling increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. S7 from Lin et al., 2015
whole organism apoptotic, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
whole organism chrd expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2,  Fig. 6 from Lin et al., 2015
whole organism dorsal region ab2-mapk labeling increased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 from Lin et al., 2015
mitotic cell cycle delayed, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 with image from Liu et al., 2011
whole organism dorsal region ab2-mapk labeling increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 from Lin et al., 2015
whole organism dharma expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 from Lin et al., 2015
whole organism bmp4 expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
blastoderm cell nucleus decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. S3 with image from Liu et al., 2011
whole organism sp5l expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism ventral region ab1-smad labeling decreased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism bmp7a expression decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism dorsal region nog1 expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
blastoderm cell cellular adhesivity blastoderm cell, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
G2/M transition of mitotic cell cycle delayed, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5 with image from Liu et al., 2011
whole organism axin2 expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism fgf8a expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 5,  Fig. 6 from Lin et al., 2015
whole organism dorsal region chrd expression increased distribution, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2,  Fig. 4,  Fig. 6 from Lin et al., 2015
epiboly involved in gastrulation with mouth forming second delayed, abnormal AB + MO1-cdk5rap3 standard conditions Fig. S1 from Lin et al., 2015
whole organism ab1-ctnnb labeling increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 7 from Lin et al., 2015
whole organism decreased life span, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 1,  Fig. S1 from Lin et al., 2015
embryonic cleavage arrested, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
blastoderm cell nucleus increased size, abnormal AB + MO1-cdk5rap3 standard conditions Fig. S3 with image from Liu et al., 2011
caudal fin ventral region aplastic/hypoplastic, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 1 from Lin et al., 2015
epiboly involved in gastrulation with mouth forming second arrested, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
blastoderm cell decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
trunk posterior region shortened, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 1 from Lin et al., 2015
embryo development arrested, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
cell population proliferation decreased occurrence, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 4 with image from Liu et al., 2011
whole organism dorsal region chrd expression increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2,  Fig. 4 from Lin et al., 2015
whole organism anterior-posterior axis decreased length, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism ventral region ab1-smad labeling decreased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 2 from Lin et al., 2015
whole organism ab2-gsk3 labeling increased amount, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 7 from Lin et al., 2015
whole organism morphology, abnormal AB + MO1-cdk5rap3 standard conditions Fig. 3 with image,  Fig. 4 with image from Liu et al., 2011
whole organism dorsal region chrd expression spatial pattern, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism chrd expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism fgf3 expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism axin2 expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism fgf8a expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism malformed, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. S8 from Lin et al., 2015
whole organism sp5l expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism dorsal region chrd expression amount, ameliorated AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. 6 from Lin et al., 2015
whole organism ventralized, abnormal AB + MO1-cdk5rap3 + MO1-ctnnb2 standard conditions Fig. S8 from Lin et al., 2015
whole organism dorsalized, exacerbated AB + MO1-cdk5rap3 + MO1-gsk3ab + MO1-gsk3ba standard conditions Fig. S9 from Lin et al., 2015
Citations
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