Morpholino

MO3-sox3

ID

ZDB-MRPHLNO-100527-3

Name

MO3-sox3

Previous Names

None

Target

sox3 (1)

Sequence

5' - TACATTCTTAAAAGTGGTGCCAAGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO3-sox3

No data available

Phenotype

Phenotype resulting from MO3-sox3

Phenotype	Fish	Figures
epibranchial ganglion decreased amount, abnormal	AB + MO3-sox3	Fig. 2 from Padanad et al., 2011
otic placode pax2a expression decreased amount, abnormal	AB + MO3-sox3 + MO4-tp53	Fig. 7 from Gou et al., 2018
otic placode pax2a expression decreased distribution, abnormal	AB + MO3-sox3 + MO4-tp53	Fig. 7 from Gou et al., 2018

Phenotype of all Fish created by or utilizing MO3-sox3

Phenotype	Fish	Conditions	Figures
epibranchial ganglion decreased amount, abnormal	AB + MO3-sox3	standard conditions	Fig. 2 from Padanad et al., 2011
otic placode pax2a expression decreased amount, abnormal	AB + MO3-sox3 + MO4-tp53	standard conditions	Fig. 7 from Gou et al., 2018
otic placode pax2a expression decreased distribution, abnormal	AB + MO3-sox3 + MO4-tp53	standard conditions	Fig. 7 from Gou et al., 2018
ectoderm pax8 expression mislocalised, abnormal	x17Tg/+ + MO3-sox3 + MO4-tp53 (AB)	heat shock	Fig. 10 from Gou et al., 2018
otic placode pax8 expression increased distribution, abnormal	x17Tg/+ + MO3-sox3 + MO4-tp53 (AB)	heat shock	Fig. 10 from Gou et al., 2018
otic placode pax8 expression spatial pattern, abnormal	x17Tg/+ + MO3-sox3 + MO4-tp53 (AB)	heat shock	Fig. 10 from Gou et al., 2018
otic placode pax8 expression increased amount, abnormal	x17Tg/+ + MO3-sox3 + MO4-tp53 (AB)	heat shock	Fig. 10 from Gou et al., 2018
whole organism lacks all parts of type facial ganglion, abnormal	AB + MO3-sox3 + MO6-pax8 + MO7-pax8	standard conditions	Fig. 2 from Padanad et al., 2011
otic vesicle decreased size, abnormal	AB + MO3-sox3 + MO6-pax8 + MO7-pax8	standard conditions	Fig. 2 from Padanad et al., 2011
whole organism lacks all parts of type glossopharyngeal ganglion, abnormal	AB + MO3-sox3 + MO6-pax8 + MO7-pax8	standard conditions	Fig. 2 from Padanad et al., 2011
whole organism lacks all parts of type vagal ganglion 2, abnormal	AB + MO3-sox3 + MO6-pax8 + MO7-pax8	standard conditions	Fig. 2 from Padanad et al., 2011
whole organism lacks all parts of type vagal ganglion 1, abnormal	AB + MO3-sox3 + MO6-pax8 + MO7-pax8	standard conditions	Fig. 2 from Padanad et al., 2011
caudal fin deformed, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox3 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
central nervous system abnormal, abnormal	WT + MO1-sox19a + MO2-sox19a + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
central nervous system abnormal, abnormal	WT + MO1-sox19b + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
gastrulation delayed, exacerbated	sox19b^m1434/m1434 + MO1-sox19a + MO2-sox19a + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Gao et al., 2022
caudal fin anatomical structure morphogenesis decreased process quality, exacerbated	sox19b^m1434/m1434 + MO1-sox19a + MO2-sox19a + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Gao et al., 2022
gastrulation delayed, exacerbated	AB/TL + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Gao et al., 2022
caudal fin anatomical structure morphogenesis decreased process quality, exacerbated	AB/TL + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Gao et al., 2022
epiboly delayed, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013 Fig. 1 from Okuda et al., 2010
whole organism wholly dorsalized, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 4 from Okuda et al., 2010
notochord broad, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
neurogenesis disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
convergent extension disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
mesoderm increased width, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 3 from Okuda et al., 2010
axis shortened, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
somite malformed, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
tail bud aplastic, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
central nervous system abnormal, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
whole organism truncated, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
neural plate increased width, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
neural plate development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 3 from Okuda et al., 2010
hindbrain development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
central nervous system development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
brain development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
head aplastic, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
anterior neural plate formation disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
prechordal plate increased distance notochord, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
whole organism embryo development arrested, abnormal	pou5f3^m793/m793 + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013

Citations