Morpholino

MO1-amotl1

ID

ZDB-MRPHLNO-091014-1

Name

MO1-amotl1

Previous Names

None

Target

amotl1 (1)

Sequence

5' - CCTCGATCTCCAACTGCAAATGTTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This MO targets exon 6 of amotl1 by interfering with the splice donor site thereby resulting in a 145 nt deletion in the mRNA which disrupts the reading frame before the coiled-coil repeats.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-amotl1

No data available

Phenotype

Phenotype resulting from MO1-amotl1

Phenotype	Fish	Figures
cell-cell adhesion disrupted, abnormal	y1Tg + MO1-amotl1	Fig. 6 from Zheng et al., 2009
intersegmental vessel decreased length, abnormal	y1Tg + MO1-amotl1	Fig. 6 from Zheng et al., 2009
intersegmental vessel blood vessel endothelial cell cellular adhesivity intersegmental vessel blood vessel endothelial cell, abnormal	y1Tg + MO1-amotl1	Fig. 6, Fig. 8 from Zheng et al., 2009

Phenotype of all Fish created by or utilizing MO1-amotl1

Phenotype	Fish	Conditions	Figures
intersegmental vessel decreased length, abnormal	y1Tg + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009
intersegmental vessel blood vessel endothelial cell cellular adhesivity intersegmental vessel blood vessel endothelial cell, abnormal	y1Tg + MO1-amotl1	standard conditions	Fig. 6, Fig. 8 from Zheng et al., 2009
cell-cell adhesion disrupted, abnormal	y1Tg + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009
eye decreased size, abnormal	axin1^tm213/+ + MO1-amot + MO1-amotl1 + MO1-amotl2a (TU)	standard conditions	Fig. 2 from Li et al., 2012
eye agenesis, abnormal	axin1^tm213/tm213 + MO1-amot + MO1-amotl1 + MO1-amotl2a (TU)	standard conditions	Fig. 2 from Li et al., 2012
intersegmental vessel decreased length, abnormal	y1Tg + MO1-amot + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009
intersegmental vessel endothelial tip cell positional polarity, abnormal	y1Tg + MO1-amot + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009
intersegmental vessel blood vessel endothelial cell cellular adhesivity intersegmental vessel blood vessel endothelial cell, abnormal	y1Tg + MO1-amot + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009
cell-cell adhesion disrupted, abnormal	y1Tg + MO1-amot + MO1-amotl1	standard conditions	Fig. 6 from Zheng et al., 2009

Citations