Morpholino

MO1-hoxb5b

ID

ZDB-MRPHLNO-090908-4

Name

MO1-hoxb5b

Previous Names

None

Target

Sequence

5' - CACATTAGCCATGGTATAAACATCTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

MO targeting the donor site of the single intron in hoxb5b efficiently abrogates splicing without affecting the hoxb5a transcript.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-hoxb5b

Expressed Gene	Anatomy	Figures
myh6	heart rudiment	Fig. 6 from Waxman et al., 2008
myh7	heart rudiment	Fig. 6 from Waxman et al., 2008

Phenotype

Phenotype resulting from MO1-hoxb5b

Phenotype	Fish	Figures
atrium cardiac muscle cell increased amount, abnormal	f2Tg + MO1-hoxb5b	Fig. 6 from Waxman et al., 2008
heart increased size, abnormal	WT + MO1-hoxb5b	Fig. 6 from Waxman et al., 2008
pericardium edematous, abnormal	WT + MO1-hoxb5b	Fig. 6 from Waxman et al., 2008
presumptive atrium primitive heart tube cardiac muscle myoblast increased amount, abnormal	WT + MO1-hoxb5b	Fig. 6 from Waxman et al., 2008

Phenotype of all Fish created by or utilizing MO1-hoxb5b

Phenotype	Fish	Conditions	Figures
heart increased size, abnormal	WT + MO1-hoxb5b	standard conditions	Fig. 6 from Waxman et al., 2008
pericardium edematous, abnormal	WT + MO1-hoxb5b	standard conditions	Fig. 6 from Waxman et al., 2008
presumptive atrium primitive heart tube cardiac muscle myoblast increased amount, abnormal	WT + MO1-hoxb5b	standard conditions	Fig. 6 from Waxman et al., 2008
atrium cardiac muscle cell increased amount, abnormal	f2Tg + MO1-hoxb5b	standard conditions	Fig. 6 from Waxman et al., 2008

Citations