Morpholino
MO1-hoxb5b
- ID
- ZDB-MRPHLNO-090908-4
- Name
- MO1-hoxb5b
- Previous Names
- None
- Target
- Sequence
-
5' - CACATTAGCCATGGTATAAACATCTC - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
MO targeting the donor site of the single intron in hoxb5b efficiently abrogates splicing without affecting the hoxb5a transcript.
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-hoxb5b
Expressed Gene | Anatomy | Figures |
---|---|---|
myh6 |
Fig. 6 ![]() |
|
myh7 |
Fig. 6 ![]() |
1 - 2 of 2
Phenotype
Phenotype resulting from MO1-hoxb5b
1 - 4 of 4
Phenotype of all Fish created by or utilizing MO1-hoxb5b
1 - 4 of 4
Citations
- D'Aniello, E., Rydeen, A.B., Anderson, J.L., Mandal, A., and Waxman, J.S. (2013) Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid. PLoS Genetics. 9(8):e1003689
- Waxman, J.S., Keegan, B.R., Roberts, R.W., Poss, K.D., and Yelon, D. (2008) Hoxb5b acts downstream of retinoic Acid signaling in the forelimb field to restrict heart field potential in zebrafish. Developmental Cell. 15(6):923-934
1 - 2 of 2
Show