Morpholino

MO2-cdx1b

ID
ZDB-MRPHLNO-090217-1
Name
MO2-cdx1b
Previous Names
  • sbMO (1)
Target
Sequence
5' - ATGTGTATTAAAGAAGCACCTGAGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking morpholino targeting the splice donor site after exon 1 of cdx1b.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-cdx1b
Expressed Gene Anatomy Figures
cdx1b Fig. 4 from Flores et al., 2008
fabp2 Fig. 5 from Flores et al., 2008
fgfrl1a Fig. 4 from Flores et al., 2008
foxa3 Fig. S1 from Flores et al., 2008
lft1 Table 1 from Wu et al., 2020
ndr2 Table 1 from Wu et al., 2020
nkx2.2a Fig. 6 from Flores et al., 2008
pitx2 Table 1 from Wu et al., 2020
slc15a1b Fig. 5 from Flores et al., 2008
Phenotype
Phenotype resulting from MO2-cdx1b
Phenotype Fish Figures
diencephalon dorsal region pitx2 expression mislocalised, abnormal AB + MO2-cdx1b Table 1 from Wu et al., 2020
diencephalon dorsal region lft1 expression mislocalised, abnormal AB + MO2-cdx1b Table 1 from Wu et al., 2020
diencephalon dorsal region ndr2 expression mislocalised, abnormal AB + MO2-cdx1b Table 1 from Wu et al., 2020
digestive tract development disrupted, abnormal WT + MO2-cdx1b Fig. 4,  Fig. 5,  Fig. 6 from Flores et al., 2008
digestive tract morphogenesis disrupted, abnormal WT + MO2-cdx1b Fig. 6 from Flores et al., 2008
enteroendocrine cell absent, abnormal WT + MO2-cdx1b Fig. 6 from Flores et al., 2008
epithelial cell differentiation disrupted, abnormal WT + MO2-cdx1b Fig. 7 from Flores et al., 2008
gut decreased thickness, abnormal WT + MO2-cdx1b Fig. 4 from Flores et al., 2008
intestinal bulb morphology, abnormal WT + MO2-cdx1b Fig. 4,  Fig. 5,  Fig. 6 from Flores et al., 2008
intestinal epithelium morphology, abnormal WT + MO2-cdx1b Fig. 6 from Flores et al., 2008
intestinal epithelium enterocyte absent, abnormal WT + MO2-cdx1b Fig. 7 from Flores et al., 2008
intestinal epithelium goblet cell absent, abnormal WT + MO2-cdx1b Fig. 7 from Flores et al., 2008
mid intestine epithelium epithelial cell cuboid, abnormal WT + MO2-cdx1b Fig. 7 from Flores et al., 2008
posterior intestine epithelium epithelial cell cuboid, abnormal WT + MO2-cdx1b Fig. 7 from Flores et al., 2008
Phenotype of all Fish created by or utilizing MO2-cdx1b
Phenotype Fish Conditions Figures
diencephalon dorsal region ndr2 expression mislocalised, abnormal AB + MO2-cdx1b control Table 1 from Wu et al., 2020
diencephalon dorsal region lft1 expression mislocalised, abnormal AB + MO2-cdx1b control Table 1 from Wu et al., 2020
diencephalon dorsal region pitx2 expression mislocalised, abnormal AB + MO2-cdx1b control Table 1 from Wu et al., 2020
mid intestine epithelium epithelial cell cuboid, abnormal WT + MO2-cdx1b standard conditions Fig. 7 from Flores et al., 2008
epithelial cell differentiation disrupted, abnormal WT + MO2-cdx1b standard conditions Fig. 7 from Flores et al., 2008
intestinal epithelium goblet cell absent, abnormal WT + MO2-cdx1b standard conditions Fig. 7 from Flores et al., 2008
intestinal bulb morphology, abnormal WT + MO2-cdx1b standard conditions Fig. 4,  Fig. 5,  Fig. 6 from Flores et al., 2008
gut decreased thickness, abnormal WT + MO2-cdx1b standard conditions Fig. 4 from Flores et al., 2008
epithelial cell proliferation process quality, abnormal WT + MO2-cdx1b chemical treatment: 5-bromo-2'-deoxyuridine Fig. 8 from Flores et al., 2008
intestinal epithelium enterocyte absent, abnormal WT + MO2-cdx1b standard conditions Fig. 7 from Flores et al., 2008
digestive tract morphogenesis disrupted, abnormal WT + MO2-cdx1b standard conditions Fig. 6 from Flores et al., 2008
mid intestine epithelium morphology, abnormal WT + MO2-cdx1b chemical treatment: 5-bromo-2'-deoxyuridine Fig. 8 from Flores et al., 2008
intestinal epithelium morphology, abnormal WT + MO2-cdx1b standard conditions Fig. 6 from Flores et al., 2008
digestive tract development disrupted, abnormal WT + MO2-cdx1b standard conditions Fig. 4,  Fig. 5,  Fig. 6 from Flores et al., 2008
enteroendocrine cell absent, abnormal WT + MO2-cdx1b standard conditions Fig. 6 from Flores et al., 2008
posterior intestine epithelium epithelial cell cuboid, abnormal WT + MO2-cdx1b standard conditions Fig. 7 from Flores et al., 2008
Citations
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