Morpholino

MO3-sox2

ID

ZDB-MRPHLNO-080329-1

Name

MO3-sox2

Previous Names

sox2-MO3 (1)

Target

sox2 (1)

Sequence

5' - GAAAGTCTACCCCACCAGCCGTAAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO3-sox2

Expressed Gene	Anatomy	Figures
sox2	whole organism	Fig. 1 from Kamachi et al., 2008

Phenotype

Phenotype resulting from MO3-sox2

Phenotype	Fish	Figures
ependymal cell cell population proliferation decreased process quality, abnormal	WT + MO3-sox2	Fig. 3 from Ogai et al., 2014

Phenotype of all Fish created by or utilizing MO3-sox2

Phenotype	Fish	Conditions	Figures
ependymal cell cell population proliferation decreased process quality, abnormal	WT + MO3-sox2	physical alteration: spinal cord	Fig. 3 from Ogai et al., 2014
ependymal cell cell population proliferation decreased process quality, abnormal	WT + MO3-sox2	standard conditions	Fig. 3 from Ogai et al., 2014
caudal fin upturned, abnormal	WT + MO3-sox2 + MO4-sox2	standard conditions	Fig. 1 from Okuda et al., 2010
posterior lateral line regeneration decreased rate, abnormal	znf32^zf743/zf743 + MO3-sox2	standard conditions	Fig. 3 from Wei et al., 2016
central nervous system abnormal, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO4-sox2	standard conditions	Fig. 1 from Okuda et al., 2010
central nervous system abnormal, abnormal	WT + MO1-sox19a + MO2-sox19a + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
central nervous system abnormal, abnormal	WT + MO1-sox19b + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
epiboly delayed, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013 Fig. 1 from Okuda et al., 2010
whole organism wholly dorsalized, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 4 from Okuda et al., 2010
notochord broad, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
neurogenesis disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
convergent extension disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
mesoderm increased width, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 3 from Okuda et al., 2010
axis shortened, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
tail bud aplastic, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
somite malformed, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
central nervous system abnormal, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 from Okuda et al., 2010
whole organism truncated, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
neural plate increased width, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
neural plate development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 3 from Okuda et al., 2010
hindbrain development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
central nervous system development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
brain development disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
head aplastic, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013
anterior neural plate formation disrupted, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 5 from Okuda et al., 2010
prechordal plate increased distance notochord, abnormal	WT + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 1 , Fig. 2 from Okuda et al., 2010
whole organism embryo development arrested, abnormal	pou5f3^m793/m793 + MO1-sox19a + MO1-sox19b + MO2-sox19a + MO2-sox19b + MO3-sox2 + MO3-sox3 + MO4-sox2 + MO4-sox3	standard conditions	Fig. 2, Fig. S8 from Leichsenring et al., 2013

Citations