Morpholino
MO2-pak2a
- ID
- ZDB-MRPHLNO-071213-4
- Name
- MO2-pak2a
- Previous Names
-
- Pak2e5i6 (1)
- Target
- Sequence
-
5' - CATGCAGTTATTCACCTGTGAAGCT - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
- None
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-pak2a
No data available
Phenotype
Phenotype resulting from MO2-pak2a
No data available
Phenotype of all Fish created by or utilizing MO2-pak2a
| Phenotype | Fish | Conditions | Figures |
|---|---|---|---|
| brain hemorrhagic, abnormal | WIK + MO2-pak2a + MO3-pak2a | standard conditions |
Fig. 2
from Liu et al., 2007 |
| cranial vasculature fragile, abnormal | WIK + MO2-pak2a + MO3-pak2a | standard conditions |
Fig. 2
from Liu et al., 2007 |
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Citations
- Thirugnanam, K., Prabhudesai, S., Van Why, E., Pan, A., Gupta, A., Foreman, K., Zennadi, R., Rarick, K.R., Nauli, S.M., Palecek, S.P., Ramchandran, R. (2022) Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability. Biochemical pharmacology. 202:115143
- Liu, J., Fraser, S.D., Faloon, P.W., Rollins, E.L., Vom Berg, J., Starovic-Subota, O., Laliberte, A.L., Chen, J.N., Serluca, F.C., and Childs, S.J. (2007) A βPix–Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104(35):13990-13995
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