ZFIN Morpholino: MO5-wnt8a

Target Location

Genome Build: GRCz11Chromosome: 14

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO5-wnt8a

No data available

Phenotype

Phenotype resulting from MO5-wnt8a

No data available

Phenotype of all Fish created by or utilizing MO5-wnt8a

Phenotype	Fish	Conditions	Figures
axis decreased length, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
notochord development disrupted, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
notochord structure, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
post-vent region mesoderm decreased size, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
trunk mesoderm decreased size, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
notochord increased width, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
axis mislocalised posteriorly, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
mesoderm formation disrupted, abnormal	AB + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a	standard conditions	Fig. 1 from Ramel et al., 2005
whole organism wholly dorsalized, abnormal	WT + MO3-wnt8a + MO5-wnt8a	standard conditions	Fig. 4 from Kapp et al., 2013
axis decreased length, abnormal	bmp2b^tc300a/+ + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
convergent extension involved in gastrulation disrupted, abnormal	bmp2b^tc300a/+ + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
axis mislocalised posteriorly, abnormal	bmp2b^tc300a/+ + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
notochord morphology, abnormal	bmp2b^tc300a/+ + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
mesoderm formation disrupted, abnormal	bmp2b^tc300a/+ + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
whole organism elongated, abnormal	bmp2b^{tc300a/tc300a} + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
whole organism morphology, abnormal	bmp2b^{tc300a/tc300a} + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
dorsal/ventral pattern formation disrupted, abnormal	bmp2b^{tc300a/tc300a} + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
polarity specification of dorsal/ventral axis disrupted, abnormal	bmp2b^{tc300a/tc300a} + MO3-wnt8a + MO4-wnt8a + MO5-wnt8a + MO6-wnt8a (TU)	standard conditions	Fig. 1 from Ramel et al., 2005
whole organism wholly ventralized, abnormal	WT + MO1-chrd + MO3-wnt8a + MO5-wnt8a	standard conditions	Fig. 4 from Kapp et al., 2013
whole organism wholly dorsalized, abnormal	ints6^p18ahub + MO3-wnt8a + MO5-wnt8a (AB/TU)	standard conditions	Fig. 4 from Kapp et al., 2013
whole organism wholly dorsalized, abnormal	ints6^p18ahub + MO1-chrd + MO3-wnt8a + MO5-wnt8a (AB/TU)	standard conditions	Fig. 4 from Kapp et al., 2013

Citations

Include unpublished citations

Kapp, L.D., Abrams, E.W., Marlow, F.L., and Mullins, M.C. (2013) The integrator complex subunit 6 (ints6) confines the dorsal organizer in vertebrate embryogenesis. PLoS Genetics. 9(10):e1003822
Baker, K.D., Ramel, M.C., and Lekven, A.C. (2010) A direct role for Wnt8 in ventrolateral mesoderm patterning. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(11):2828-2836
Ramel, M.C., Buckles, G.R., Baker, K.D., and Lekven, A.C. (2005) WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation. Developmental Biology. 287(2):237-248

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