Morpholino
MO3-ift88
- ID
- ZDB-MRPHLNO-050513-1
- Name
- MO3-ift88
- Previous Names
- Target
- Sequence
-
5' - GCCTTATTAAACAGAAATACTCCCA - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Targeted to 5' UTR of ift88 (ttc10). This morpholino was used in studies reported in ZDB-PUB-080527-11 but was cited with a typo in the Materials and Methods that left off the first three nucleotides (GCC).
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-ift88
No data available
Phenotype
Phenotype resulting from MO3-ift88
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Phenotype of all Fish created by or utilizing MO3-ift88
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Citations
- Lepanto, P., Davison, C., Casanova, G., Badano, J.L., Zolessi, F.R. (2016) Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish. Neural Development. 11:10
- Samsa, L.A., Givens, C., Tzima, E., Stainier, D.Y., Qian, L., Liu, J. (2015) Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development (Cambridge, England). 142:4080-91
- Goetz, J.G., Steed, E., Ferreira, R.R., Roth, S., Ramspacher, C., Boselli, F., Charvin, G., Liebling, M., Wyart, C., Schwab, Y., Vermot, J. (2014) Endothelial cilia mediate low flow sensing during zebrafish vascular development. Cell Reports. 6:799-808
- Lunt, S.C., Haynes, T., and Perkins, B.D. (2009) Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(7):1744-1759
- Krock, B.L., and Perkins, B.D. (2008) The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors. Journal of Cell Science. 121(Pt 11):1907-1915
- Tsujikawa, M., and Malicki, J. (2004) Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons. Neuron. 42(5):703-716
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