Gene
bin1b
- ID
- ZDB-GENE-030425-1
- Name
- bridging integrator 1b
- Symbol
- bin1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have phospholipid binding activity and tau protein binding activity. Involved in cardiac muscle contraction. Predicted to localize to plasma membrane and synaptic vesicle. Is expressed in adaxial cell; cardiovascular system; musculature system; and somite. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Orthologous to human BIN1 (bridging integrator 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb57 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Hong et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
centronuclear myopathy 2 | Alliance | Centronuclear myopathy 2 | 255200 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | AH/BAR domain superfamily | Amphiphysin | Amphiphysin 2, SH3 domain | BAR domain | SH3 domain | SH3-like domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AT31
|
543 | ||||||
UniProtKB:A0A8M3B348
|
533 | ||||||
UniProtKB:A0A8M9QFB8
|
407 | ||||||
UniProtKB:A0A8M9QAA8
|
396 | ||||||
UniProtKB:A0A8M3AT25
|
564 | ||||||
UniProtKB:A0A8M3B066
|
451 | ||||||
UniProtKB:A0A8M3BA55
|
545 | ||||||
UniProtKB:A0A2R8QMI5
|
576 | ||||||
UniProtKB:F1QRX4
|
364 | ||||||
UniProtKB:A0A8M3B064
|
565 | ||||||
UniProtKB:A0A8M3AT30
|
440 | ||||||
UniProtKB:A0A8M9PZM7
|
568 |
Interactions and Pathways
No data available
Plasmids