ZFIN ID: ZDB-LAB-040318-2
Jing-Wei Xiong Lab
PI/Director: Xiong, Jing-Wei
Contact Person: Xiong, Jing-Wei
Email: jingwei_xiong@pku.edu.cn
URL: http://www.imm.pku.edu.cn/
Address: Laboratory of Cardiovascular Development Institute of Molecular Medicine Peking University New Life Science Research Building Room 102 Mail Box 140 Beijing 100871 China
Country: China
Phone: 010-6276-6239
Fax:
Line Designation: pku


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 18 genomic features


STATEMENT OF RESEARCH INTERESTS
Cardiovascular development and regeneration


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Lei, L., Yan, S.Y., Yang, R., Chen, J.Y., Li, Y., Bu, Y., Chang, N., Zhou, Q., Zhu, X., Li, C.Y., Xiong, J.W. (2017) Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors. Nucleic acids research. 45(6):3422-3436
Yang, R., Zhang, Y., Huang, D., Luo, X., Zhang, L., Zhu, X., Zhang, X., Liu, Z., Han, J., Xiong, J.W. (2017) Miconazole protects blood vessels from matrix metalloproteinase 9-dependent rupture and hemorrhage. Disease models & mechanisms. 10(3):337-348
Wang, F., Gao, L., Meng, L.Y., Xie, J.M., Xiong, J.W., and Luo, Y. (2016) A Neutralized Noncharged Polyethylenimine-Based System for Efficient Delivery of siRNA into Heart without Toxicity. ACS applied materials & interfaces. 8(49):33529-33538
Xiao, C., Gao, L., Hou, Y., Xu, C., Chang, N., Wang, F., Hu, K., He, A., Luo, Y., Wang, J., Peng, J., Tang, F., Zhu, X., Xiong, J.W. (2016) Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish. Nature communications. 7:13787
Cheng, F., Miao, L., Wu, Q., Gong, X., Xiong, J., Zhang, J. (2016) Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish. Development (Cambridge, England). 143(19):3522-3531
Wu, Q., Zhang, J., Koh, W., Yu, Q., Zhu, X., Amsterdam, A., Davis, G.E., Arnaout, M.A., Xiong, J.W. (2015) Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(12):4989-5005
Diao, J., Wang, H., Chang, N., Zhou, X.H., Zhu, X., Wang, J., Xiong, J.W. (2015) PEG-PLA Nanoparticles facilitate siRNA knockdown in adult zebrafish heart. Developmental Biology. 406(2):196-202
Zhang, M., Sun, T., Jian, C., Lei, L., Han, P., Lv, Q., Yang, R., Zhou, X., Xu, J., Hu, Y., Men, Y., Huang, Y., Zhang, C., Zhu, X., Wang, X., Cheng, H., Xiong, J.W. (2015) Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish. PLoS One. 10:e0132567
Gao, H., Bu, Y., Wu, Q., Wang, X., Chang, N., Lei, L., Chen, S., Liu, D., Zhu, X., Hu, K., Xiong, J.W. (2015) Mecp2 regulates neural cell differentiation by suppressing the Id1-Her2/Hes5 axis in zebrafish. Journal of Cell Science. 128(12):2340-50
Yang, R., Yan, S., Zhu, X., Li, C.Y., Liu, Z., Xiong, J.W. (2015) Antimalarial drug artemisinin depletes erythrocytes by activating apoptotic pathways in zebrafish. Experimental hematology. 43(4):331-341.e8
Han, P., Zhou, X.H., Chang, N., Xiao, C.L., Yan, S., Ren, H., Yang, X.Z., Zhang, M.L., Wu, Q., Tang, B., Diao, J.P., Zhu, X., Zhang, C., Li, C.Y., Cheng, H., Xiong, J.W. (2014) Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Research. 24(9):1091-107
Bu, Y., Su, F., Wang, X., Gao, H., Lei, L., Chang, N., Wu, Q., Hu, K., Zhu, X., Chang, Z., Meng, K., Xiong, J.W. (2014) Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. Journal of Cell Science. 127(Pt 12):2761-70
Yan, B., Han, P., Pan, L., Lu, W., Xiong, J., Zhang, M., Zhang, W., Li, L., Wen, Z. (2014) Il-1beta and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury-Induced Inflammation Model. Journal of immunology (Baltimore, Md. : 1950). 192(12):5998-6008
Zhu, Z., Chen, J., Xiong, J.W., Peng, J. (2014) Haploinsufficiency of Def Activates p53-Dependent TGFbeta Signalling and Causes Scar Formation after Partial Hepatectomy. PLoS One. 9:e96576
Xiong, J.W., and Chang N.N. (2013) Recent advances in heart regeneration. Birth defects research. Part C, Embryo today : reviews. 99(3):160-169
Chang, N., Sun, C., Gao, L., Zhu, D., Xu, X., Zhu, X., Xiong, J.W., and Xi, J.J. (2013) Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Cell Research. 23(4):465-472
Wang, X., Yu, Q., Wu, Q., Bu, Y., Changm, N.N., Yan, S., Zhou, X.H., Zhu, X., and Xiong, J.W. (2013) Genetic Interaction between pku300 and fbn2b Controls Endocardial Cell Proliferation and Valve Development in Zebrafish. Journal of Cell Science. 126(Pt 6):1381-91
Zhen, Y.S., Wu, Q., Xiao, C.L., Chang, N.N., Wang, X., Lei, L., Zhu, X., and Xiong, J.W. (2012) Overlapping cardiac programs in heart development and regeneration. Journal of Genetic Genomics. 39(9):443-449
Fei, P., Yu, Z., Wang, X., Lu, P.J., Fu, Y., He, Z., Xiong, J., and Huang, Y. (2012) High dynamic range optical projection tomography (HDR-OPT). Optics express. 20(8):8824-8836
Wang, W., Ni, L., Yu, Q., Xiong, J., Liu, H.C., and Rosenwaks, Z. (2010) Expression of the Lycat gene in the mouse cardiovascular and female reproductive systems. Developmental dynamics : an official publication of the American Association of Anatomists. 239(6):1827-1837
Xiong, J.W., Yu, Q., Zhang, J., and Mably, J.D. (2008) An Acyltransferase Controls the Generation of Hematopoietic and Endothelial Lineages in Zebrafish. Circulation research. 102(9):1057-1064
Xiong, J.W. (2008) Molecular and developmental biology of the hemangioblast. Developmental dynamics : an official publication of the American Association of Anatomists. 237(5):1218-1231
Wang, C., Faloon, P.W., Tan, Z., Lv, Y., Zhang, P., Ge, Y., Deng, H., and Xiong, J.W. (2007) Mouse lycat controls the development of hematopoietic and endothelial lineages during in vitro ES cell differentiation. Blood. 110(10):3601-3609
Moser, M., Yu, Q., Bode, C., Xiong, J.W., and Patterson, C. (2007) BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. Journal of Molecular and Cellular Cardiology. 43(3):243-253
Li, X., Xiong, J.W., Shelley, C.S., Park, H., and Arnaout, M.A. (2006) The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells. Development (Cambridge, England). 133(18):3641-3650