Fig. 2
- ID
- ZDB-IMAGE-260601-2
- Genes
- Antibodies
- Publication
- Bertrand et al., 2026 - ⍺TAT1-dependent microtubule acetylation is required for touch sensation in zebrafish but not for cilia-driven morphogenesis
- All Figures
- Figures for Bertrand et al., 2026
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Fig. 2 ⍺TAT1 is required for ⍺-tubK40Ac in cilia, but loss of ⍺TAT1 does not impair cilia function (A) Immunofluorescence of the central canal in 24 hpf wild-type sibling and atat1 mutant embryos stained for ⍺-tubK40Ac and ⍺-tub. Arrowheads indicate cilia. Scale bar, 10 μm. (B) Superplots of central canal cilia length. Dots represent individual cilia; triangles indicate per-fish means (n = 3 per genotype). Bars show mean ± standard deviation. P = 0.74 (unpaired t-test). (C) Central canal cilia density, defined as the number of cilia per 10 μm. Bars show mean ± standard deviation. P = 0.69 (unpaired t-test). (D) Central canal cilia beat frequency (CBF). Bars show mean ± standard deviation. P = 0.92 (Mann-Whitney U test). (E) Heatmap of CBF measurements shown in (D). Scale bar, 10 μm. (F) Representative frame from live imaging of Sspo-GFP, which labels the RF, in the central canal. Scale bar, 10 μm. (G) Immunofluorescence of the olfactory placode at 6 dpf in wild-type sibling and atat1 mutant embryos stained for ⍺-tubK40Ac and ⍺-tub. Scale bar, 5 μm. (H) Heatmap of olfactory placode CBF measurements, with the key as given in (E). Scale bar, 5 μm.
Reprinted from Developmental Biology, 535, Bertrand, S.G., Grimes, D.T., ⍺TAT1-dependent microtubule acetylation is required for touch sensation in zebrafish but not for cilia-driven morphogenesis, 124-132, Copyright (2026) with permission from Elsevier. Full text @ Dev. Biol.