IMAGE

Figure 7.

ID
ZDB-IMAGE-260530-42
Publication
Pirzada et al., 2026 - Loss of U11/U12 spliceosome gene ZCRB1 leads to aberrant ciliogenesis and WNT signaling
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Figures for Pirzada et al., 2026
Image
Figure Caption

Figure 7. Model depicting the role of ZCRB1 in ciliogenesis, WNT signaling, and vertebrate development.
Hypomorphic levels of ZCRB1/Zcrb1 lead to altered splicing of ciliary genes with minor introns leading to loss of primary cilia and coinciding hyperactivation of WNT signaling causing developmental abnormalities. The image was generated by BioRender software.

Acknowledgments
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