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Fig. 2.

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Publication: Dockery et al., 2026 - Genes for 5'mRNA cap binding proteins, eif4ea and eif4eb, have alternative roles during heart regeneration
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Fig. 2. The eif4e1c gene can fully compensate for complete loss of both canonical cap binding orthologs. (A) Table shows survival of Δeif4ea/Δeif4eb double mutants at Mendelian ratios. R is the critical value and the χ² statistics are at the bottom. (B) Weights of adult siblings that are Δeif4ea or Δeif4eb. There is no significant difference (ANOVA p-value = 0.085). (C) Lengths of adult siblings that are Δeif4ea or Δeif4eb compared to wildtype. There is no significant difference (ANOVA p-value = 0.130). (D) CM numbers of wildtype (black) and Δeif4ea/Δeif4eb double mutants (pink) are not significant (Welch's t-test p-value = 0.11). Error bars represent mean ± s.e.m. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

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Reprinted from Developmental Biology, 534, Dockery, R., Zevallos, M., McNulty, C., Zecchino, T., Ratermann, R., White, R., Kolonay, D., Baskin, K., Goldman, J.A., Genes for 5'mRNA cap binding proteins, eif4ea and eif4eb, have alternative roles during heart regeneration, 50-60, Copyright (2026) with permission from Elsevier. Full text @ Dev. Biol.