IMAGE

Fig. 3.

ID: ZDB-IMAGE-260401-43
Publication: Karchner et al., 2026 - Using fish models to understand the role of aryl hydrocarbon receptor (AHR)-interacting protein (AIP) in controlling sensitivity and resistance to dioxin-like compounds in vivo
All Figures: Figures for Karchner et al., 2026

Image

Figure Caption

Fig. 3.

Survival of AIP mutant fish. A) Killifish. Heterozygous aip^wh71 killifish were crossed and dead or moribund embryos and larvae were sampled and genotyped as described in Materials and Methods. At the end of 2 mo, all surviving larvae were fin-clipped and genotyped. The graph shows combined results from 2 independent clutches, totaling 162 larvae (56 wild-type, 67 heterozygous, 32 homozygous). B, C) Zebrafish. Heterozygous aip^wh86 (B) and aip^wh239 (C) zebrafish were crossed and dead or moribund embryos and larvae were sampled and genotyped as described in Materials and Methods. After 14 dpf, all survival larvae were genotyped. The graph shows representative results from 4 or 5 clutches (Table S2). Abbreviations: WT: Wild-type, HET: Heterozygous, HMZ: Homozygous, dpf: Days postfertilization.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Toxicol. Sci.