IMAGE

Fig. 2

ID

ZDB-IMAGE-251231-3

Genes

EGFP

Publication

Shi et al., 2025 - Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis

All Figures

Figures for Shi et al., 2025

Image

Figure Caption

Fig. 2

Minoxidil inhibits cd41:eGFP^low HSPCs proliferation in zebrafish embryos without triggering apoptosis. A Double staining of bromo deoxyuridine (BrdU) and cd41:eGFP cells in CHT region at 3 dpf. White arrowheads indicate cd41:eGFP^low/BrdU double positive cells, yellow arrowheads indicate cd41:eGFP^high/BrdU double positive cells. Scale bars: 25 μm. B Statistics result of the percentage of cd41:eGFP^low/BrdU double positive cells in total cd41:eGFP^low cells at 3 dpf (Student’s t-test, n = 14 and n = 8, respectively; mean ± SD; *P < 0.05). C Statistics result of the percentage of cd41:eGFP^high/BrdU double positive cells in total cd41:eGFP^high cells at 3 dpf (Student’s t-test, n = 14 and n = 8, respectively; mean ± SD; ns, not significant). D Double staining of TUNEL and cd41:eGFP cells in CHT region at 3 dpf. White arrowheads indicate cd41:eGFP^low/TUNEL double-positive cells. Scale bars: 25 μm. E Quantification of the percentage of cd41:eGFP^low/TUNEL double positive cells in total cd41:eGFP^low cells at 3 dpf (Student’s t-test, n = 13; mean ± SD; ns, not significant). F Quantification of the percentage of cd41:eGFP^high/TUNEL double positive cells in total cd41:eGFP^high cells at 3 dpf (Student’s t-test, n = 13; mean ± SD; ns, not significant)

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Commun. Signal.