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Figure 2
Cortisol and dexamethasone had an higherpotency and efficacy on zfMR than on hMR
Dose-response curves of aldosterone, dexamethasone, cortisol, and bimedrazole in UG5LN-GAL4-hMR (A) and UG5LN-GAL4-zfMR cells (B). Results are expressed as the percentage of the maximum luciferase activity induced by 10−8 M aldosterone. The curves are presented as a non-linear regression; log (ligand) versus response. EC50 values (10−9 M) are shown in
Data are presented as means ± SD values. n (replicates per experiment) = 4 per group.
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