IMAGE

Fig. 5

ID

ZDB-IMAGE-251106-41

Genes

tph2

Antibodies

Ab2-RFP

Publication

Li et al., 2025 - A zebrafish model of chronic heart failure caused by protein aggregation in heart valves

All Figures

Figures for Li et al., 2025

Image

Figure Caption

Fig. 5 Red fluorescent protein (RFP) accumulation and its implications in the atrioventricular (AV) valve of tomato zebrafish.

A Bright-field image (left) and RFP fluorescence (right) from WT and tomato zebrafish hearts. Scale bar, 1 mm. B Illustration of RFP expression (shown in red) in the AV and bulboventricular (BV) valves of tomato zebrafish. A atrium, V ventricle, AV valve atrioventricular valve, BV valve bulboventricular valve. C Immunohistochemical detection of RFP (red) expression in the AV valve region of WT and tomato zebrafish at 3 months post-fertilization (mpf). DAPI (blue) staining of cell nuclei. White dotted lines: atrioventricular (AV) valves. Scale bar, 50 μm. Dtph2 expression in the AV valve region of two WT zebrafish was detected by section in situ hybridization at 3 mpf. Black dotted lines: atrioventricular (AV) valves. Scale bar, 50 μm. E Schematic of Cre mRNA injection. Black arrows: heart position. Scale bar, 10 mm.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Commun Biol