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Fig 5

ID
ZDB-IMAGE-251030-64
Source
Figures for Goering et al., 2025
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Figure Caption

Fig 5 Model of the mechanism of action of 3-HK improving macrophage function during in vivo infection.

3-HK, given exogenously or produced endogenously in the kynurenine pathway by Kmo, antagonizes kainate receptors to reduce the intracellular burden of S. Typhimurium in macrophages through enhanced lysosomal acidification. Schematic created with BioRender [25].

Acknowledgments
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