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Fig. 4 hcn2b KO is more active during the light hours of the day. A. 24 h locomotor activity of larvae (7 dpf). B. Statistically significant differences were observed in the locomotor activity of hcn2b mutants during the light-cycle but not in the dark-cycle. Data expressed as the means ± SEM and analyzed by Kruskal–Wallis n = 27, p < 0.05 (*). C. Average swimming speed during a 24 h cycle. D. Consistent with differences in traveling distance, in average hcn2b KO swam faster during the light cycle. Data expressed as the means ± SEM and analyzed by Kruskal–Wallis n = 27, p < 0.05 (*), p < 0.01 (**).
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