ZFIN Image: Xiang et al., 2025, Fig. 7

Image

Figure Caption

Fig. 7

miRNA-130b-3p overexpression causes impaired osteogenesis and axial curvature deformity in zebrafish.a. Development of zebrafish embryos after microinjection of miRNA-130b-3p mimic (n = 100) b. Imaging of zebrafish with axial curvature deformity c. Alizarin Red S staining shows delayed vertebral development in zebrafish after miRNA-130b-3p overexpression d. Statistical analysis of vertebral development in zebrafish at day 7(n = 10) e. Expression levels of dre-miR-130b in zebrafish after miRNA-130b-3p mimic microinjection are elevated(n = 5) f. Expression levels of igf1 in zebrafish decrease after miRNA-130b-3p mimic microinjection(n = 5) g. Expression levels of col1a2 in zebrafish decrease after miRNA-130b-3p mimic microinjection(n = 5) h. Expression levels of ocn in zebrafish decrease after miRNA-130b-3p mimic microinjection(n = 5) ***:p<0.001; **:p<0.01; *:p<0.05

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell. Mol. Life Sci.