|
Fig. 1 Quantification of 11-KT following exposure to BPS. (A) Plasma levels of 11-Ketotestosterone (11-KT) (ng/mL of plasma) in male zebrafish after 14 days of exposure to Vehicle (DMSO, control) or BPS (0.5 µg/L). (B) Release of 11-KT by zebrafish testicular explants previously treated with DMSO or BPS (0.5 µg/L) for 14 days. Testes were incubated in culture media (L-15) with or without Fsh (200 ng/mL) for 48 h. Bars represent the mean ± standard error of the mean (SEM) (n = 8). Different letters denote significant differences (p < 0.05) between groups. (***) indicates a significant difference (p < 0.001).Parte superior do formulário.