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Fig. 7 ADB-FUBINACA induced changes in the transcription levels of related genes. (A) Expression of metabolism-related genes (lpcat3 and gclc). (B) Expression of inflammation-related genes (il-6, il-8, and tnfa). (C) Expression of cardiac development-related genes (nkx2.5, nppa, gata4, and tbx2b). (D) Schematic of developmental toxicity in zebrafish embryos after ADB-FUBINACA exposure. This schematic was drawn by Figdraw (https://www.figdraw.com/). (ID: RYTIYcb092). The data were presented as mean ± S.D. of three independent experiments (n = 30). * p < 0.05, ** p < 0.01, *** p < 0.001.
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