ZFIN Image: Hark et al., 2025, Fig. 2

Image

Figure Caption

Fig. 2

Generation and investigation of transgenic alpl knockout zebrafish line. (A) Schematic drawing of the genomic region on chromosome 11 deleted in alpl^wue7 zebrafish larvae. The inserted alpl promoter deletion is including the alpl promoter region, together with exon 1 and parts of 5’UTR and intron 1. (B) Bone and cartilage double-stainings of 120 hpf transgenic zebrafish larvae display slightly changed craniofacial development in the neurocranium and viscerocranium. Bone (red) and cartilage (blue). Two individuals representing the same genotype, but different phenotype severities are shown for hetero- and homozygotes. wildtype = alpl^+/+; heterozygous = alpl^wue7/+; homozygous = alpl^wue7/wue7.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.