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Fig. 4 Concentration-effect curves of benzbromarone (BEN; IC50: 5.95 µM ± 1.49 µM; A), dipyridamole (DIP; IC50: 8.09 µM ± 0.28 µM; B), MK-571 (MK; IC50: 6.78 µM ± 0.39 µM; C), and pranlukast (PRA; IC50: 4.29 µM ± 0.60 µM; D) against drOatp1d1 applying a cell-based functional assay using radiolabeled [3H]BSP and stably transfected HEK-drOatp1d1 cells and the respective HEK-Co cells [7]. Shown is mean ± SEM of at least four independent experiments.
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