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Fig. 2 Concentration-effect curves of the model drOatp1d1 substrate bromosulfophthaleine (BSP; A) [14] and the newly established drOatp1d1 inhibitor cyclosporine A (CYC; B) [14] determined in a cell-based functional assay using radiolabeled [3H]BSP and stably transfected HEK-drOatp1d1 cells and respective HEK-Co cells [7]. Shown is mean ± standard error of the mean (SEM) of at least four independent experiments.
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