ZFIN Image: Malarz et al., 2025, Fig. 3

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Figure Caption

Fig. 3

The time-dependent impact of the tested IS20 derivative on ROS (navy blue bars) and GSH (green bars) levels in the K562 and U-251 cells (A). The mRNA expression of MnSOD, and CAT genes in the K562 and U-251 cells after incubation with IS20 in kinetic experiments (B). The data were normalized to the control–untreated cells and analyzed using the unpaired t-test: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to the control. The results are presented as the mean ± SD of several independent experiments (n = 5). The red dashed lines indicate the standardized levels of ROS and GSH in the control, which is taken to be 100%.

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