ZFIN Image: Disner et al., 2025, Figure 7

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Figure 7

Network and enrichment analysis of signaling pathway-related genes overexpressed during injury-induced inflammation in zebrafish larvae treated with TnP compared to untreated control. (A) Protein-protein interaction (PPI) networks of 66 differentially overexpressed genes (p_adj < 0.05). The PPI network was performed in STRING on Cytoscape, and each subnetwork was evaluated in the software to provide the main functional enrichment term through STRING. The bigger the circle, the lower the adjusted p-value. Singletons were omitted from the network. (B) Functional enrichment analysis focusing on the overexpressed genes list (62 DAVID IDs) related to signaling pathways using the DAVID software. Terms were considered significant if the adjusted p-value was less than 0.05 and the gene count at least 3.

Acknowledgments

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