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Fig. 5a PRPS1 knockdown increases apoptosis in HEI-OC1 cells. (a, b) Apoptotic cells detected by flow cytometry in each group. (c) Western blot analysis of proapoptotic proteins Bax, Cytochrome c, Smac/Diablo, and antiapoptotic protein Bcl-2, with tubulin as the internal control. (d) Quantification of protein expression levels from (c). Data are presented as mean ± SD from three independent experiments. ∗∗∗p < 0.001 and ∗∗∗∗p < 0.0001 compared with si-CTRL; ####p < 0.0001 compared with si-PRPS1.
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Full text @ Hum. Mutat.