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Fig. 4 The therapeutic effect of Mulberroside C (MC) on leukopenia mice. (A) Timeline of the KM mice intervention protocol. Effect of MC (2–8 mg/kg) or granulocyte colony-stimulating factor (G-CSF, 25 μg/kg) in irradiated or cyclophosphamide-treated KM mice. In irradiated KM mice, n = 8, (B) peripheral white blood cell counts, (C) peripheral neutrophil counts, (D) peripheral monocyte counts, and (E) peripheral lymphocyte counts. In cyclophosphamide-treated KM mice, n = 6, (F) peripheral white blood cell counts, (G) peripheral neutrophil counts, (H) peripheral monocyte counts, and (I) peripheral lymphocyte counts. Data are expressed as the mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 versus the model group.