ZFIN Image: Yamashita et al., 2025, Fig. 4

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Figure Caption

Fig. 4

RNA-seq analysis revealed that DNAJC7 expression was decreased in the motor cortex of the FALS cases with the DNAJC7 variant. a Bar graph showing the number of genes that were upregulated or downregulated in patients with FALS (IV-1, IV-4) compared to normal controls. b Waterfall plot depicting the top ten upregulated and downregulated genes in patients with FALS. c Volcano plot illustrating the statistical significance against the fold change for gene expression in patients with FALS. FALS, familial amyotrophic lateral sclerosis; RNA-seq, RNA sequencing

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Acta Neuropathol.