ZFIN Image: Mo et al., 2025, Figure 3.

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Figure Caption

Figure 3.

Effects of PMMEXOs on melanin secretion and tyrosinase activity in B16F10 melanoma cells. (A) PMMEXOs (0–300 μg/mL) treated B16F10 cells at 24 h, 48 h, 72 h relative cell viability, n = 6. (B) Microscopic images were collected every 24 h. Scale bars = 200 μm, n = 3. (C) Number of cells per 24 h, n = 5. (D) Change in medium colour after each well of drug treatment. Intracellular (E) and extracellular (F) measurements of melanin content, n = 6. (G) Evaluation of tyrosinase activity after PMMEXOs treatment, n = 6. Data were expressed as mean ± SD, and one-way analysis of variance was used for statistical significance. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 compared with α-MSH model group, ####P < 0.0001 compared with the blank group.

Acknowledgments

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