ZFIN Image: Mo et al., 2025, Figure 9.

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Figure Caption

Figure 9.

PMMEXOs reduces melanin production by activating the NF-κB signaling pathway. (A) The translocation of NF-κB p-65 from cytoplasm to nucleus of B16-F10 cells after different drug stimulation was detected by immunofluorescence assay. The arrow indicates the translocation of NF-κB p-65 from cytoplasm to nucleus. Fluorescent of NF-κB p-65 proteins, nuclei stained with DAPI. Scale bars = 50 μm. WB detection of NF-κB p-P65 (B) and IκB-α (C) protein expression. The relative protein expression level of NF-κB p-P65 (D) and IκB-α (E) were quantitatively analyzed. n = 3. Data are expressed as mean ± SD, one-way analysis of variance was used for statistical significance. n. s. no significant difference observed between groups. *P < 0.05, **P < 0. 01, ***P < 0.001, ****P < 0.0001.

Acknowledgments

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