ZFIN Image: Zhao et al., 2025, Fig. 1

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Figure Caption

Fig. 1

Phylogenetic tree of divergence times and expansion of gene families.

A: Evolutionary analysis of FoxO divergence times, showing the distribution of FoxO gene families in different species. foxo1a is highly conserved among jawed vertebrates, and its first appearance in the vertebrate genome coincides with the emergence of jawed vertebrates.

B: Analysis of gene family expansion, with a significant expansion of the FoxO gene family.

C: Distribution of FoxO gene family members on zebrafish chromosomes.

D: Synteny analysis between zebrafish and lamprey.

E: Phylogenetic tree of the FoxO family proteins.

F: Early expression of the zebrafish foxo1a gene.

Acknowledgments

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