Image
|
Figure Caption
Fig. 7 Human RLBP1 represents a good target for a humanized zebrafish approach. (A) Schematic of the humanized zebrafish lines approach used in this study. (B) Alignment of Cralbp protein sequences using the TCoffee alignment tool. Domains mapped to these sequences manually from the NCBI conserved domain search tool. Pathogenic mutations in CRALBP are taken from [6]. (C) Structural model of human CRALBP and zebrafish paralogs created using the SWISS-MODEL web tool. (D) Structural model of human CRALBP and missense variants p.R151Q and p.A237V using the SWISS-MODEL web tool.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ FASEB J.