Quantitative analysis of neurotransmitter alterations in zebrafish larvae following lurasidone exposure. (A) Box plots showing changes in GABAergic system components (glutamate, GABA, glutamine, and glycine). (B) Alterations in serotonergic pathway metabolites (5-hydroxyindole-3-acetic acid, 5-hydroxy-L-tryptophan, and serotonin). (C) Changes in dopaminergic system components (dopamine, 3-methoxytyramine, metanephrine, normetanephrine, tyramine, and epinephrine). (D) Effect on cholinergic neurotransmitter (acetylcholine). (E) Impact on histaminergic system (histamine). P-values were calculated using Student’s t-test. Data are presented as mean ± SE.
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