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Fig. 5 Abnormal neurogenesis in the anterior neural plate in her6 mutants. Schematic views for the anterior neural plate (A) and the enlarged view of the central hindbrain (B), showing abnormal expression of proneural cluster domain (PCD) genes in her6 mutants (cf. Fig. 4). Dorsal views with anterior to the top. (Left) Purple indicates her6 expression, while black dashed lines indicate the extent of her9 expression. (Middle and right) Expression patterns of PCD genes in wild-type (middle) and in her6 homozygotes (right). PCD gene expression was ectopically activated or enhanced in ANB, vrc/drc/vcc, r3 (IPCD-r3), and midline of the r1/2– r4 region (md-IPCS-r3/5). In the IPCD-r3, ectopic expression is often seen in its medial portion (medial IPCD-r3, m-IPCD-r3), whereas rarely in its lateral portion (lateral IPCD, l-IPCDS-r3). See the legend to Fig. 1 for abbreviations.