IMAGE

Fig. 1

ID

ZDB-IMAGE-250708-47

Genes

fzd5

Publication

Monfries et al., 2025 - frizzled5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma

All Figures

Figures for Monfries et al., 2025

Image

Figure Caption

Fig. 1 fzd5 is expressed in the optic primordium throughout eye formation. (A-D) Dorsal (A-C) or ventral (D) views, with anterior to the left, at the stage indicated in each panel. Dotted outlines in A and B highlight the optic vesicles. Brackets in D highlight the ciliary marginal zone (CMZ). (E) Schematic of the transcription activator-like effector nucleases (TALENs; t1 and t2) and guide RNAs (g1 to g4) used to generate the fzd5 mutant alleles for this study, and their predicted protein products. aa, amino acids; hpf, h post-fertilisation; hyp, hypothalamus; ov, optic vesicles; vt, ventral telencephalon. Scale bars: 100 µm.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.