ZFIN Image: Lin et al., 2025, Figure 6

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Figure 6

Biofilm clearance by combining phiLCL12 and 1/2 MIC of imipenem over time. After 12 h of P. aeruginosa LCL12 biofilm growth at 2 × 10⁷ CFU, varying concentrations of phiLCL12 and 1/2 MIC of imipenem were applied to the experimental groups. (A) Qualitative analysis showed no visible biofilms on the coverslips after 18 h of treatment with 2 × 10⁹ PFU of phiLCL12. Quantitative analysis of biofilm clearance over time, with evaluations conducted at 6 (B), 12 (C), and 18 (D) h. All the results were obtained from three independent experiments. On the left panel, *** represents the significance of the control group versus treated groups assessed by one-way ANOVA, *** indicates p < 0.001. On the right panel, ## and ### represent the significance of the phage-only group versus the PAS group, which is assessed by two-way ANOVA. “###” indicates p < 0.001, “##” indicates p < 0.01.

Acknowledgments

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