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Fig. 10 pERK (green)/tERK (red)-signals of MK-801-induced larval zebrafish habenula after the startle habituation paradigm. (A) Sample illustration of three z planes separated by 7 μM for the MK (left), MKJNJ (middle) and MKTAK (right) groups. White scale bar: 20 μM (B, C, D) pERK/tERK values of three planes arranged the ventral side of the left habenula (labeled as left) to the ventral side of the right habenula (labeled as right). (E) Cumulative distribution in fractions of pERK/tERK values of the MK, MKJNJ and MKTAK groups. (F) Comparison of combined planes pERK/tERK between groups. (G) Linear regression for left habenula (left) and right habenula (right). R squared of the fitted line were tabled. Kruskal–Wallis test followed by Dunn's multiple comparison test were conducted. * indicated p < 0.05, *** indicated p < 0.001, and ns indicated non-significant difference.