ZFIN Image: Wu et al., 2025, Fig. 8.

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Figure Caption

Fig. 8.

Model for mitotic and cellular events that occur during KV development. (A) Anterior KV precursor cells are stimulated by FGF to enter mitosis. (B) KV cells begin to form small rosettes, comprising both post-mitotic cells and those still dividing, with mitotic activity concentrated anteriorly. (C) Cells transition into a single rosette, with anterior post-mitotic cells contributing cytokinetic bridges toward the rosette center. (D) The rosette matures into a ciliated KV with a fluid-filled lumen, and post-mitotic cells become evenly distributed. MTs, microtubules.

Acknowledgments

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